Wonder Drug?
Resveratrol is found in the skin of red grapes and is a constituent of red wine, but also in many other foodstuffs.It is a phytoalexin produced naturally by several plants when under attack by pathogens such as bacteria or fungi. It is currently marketed as one of many anti aging products.
It is newly identified and is still being researched and explored, however, scientists are very optimistic about the health properties associated with this unique nutrient.
Resveratrol was firstly obtained from the roots of Japanese Knotweed. It can balance the body hormones and also counteracts the oxidization of melanin cells, the condition which initiates aging spots and also triggers collagen production.
By interfering with all three stages of carcinogenesis " initiation, promotion and progression, resveratrol has been found to induce cell cycle arrest when added to cancer cells grown in culture also it has been found to inhibit proliferation and induce apoptosis in a number of cancer cell lines.
In vitro resveratrol interacts with multiple molecular targets and has positive effects on the cells of breast, skin, gastric, colon, esophageal, prostate, pancreatic cancer, and leukemia. The strongest evidence of anti-cancer action of resveratrol exists for tumors it can come into direct contact with, such as skin and gastrointestinal tract tumors. For other cancers, the evidence is uncertain, even if massive doses of resveratrol are used.
In theory resveratrol could help against diseases such as Huntington's disease and Alzheimer's disease as it was reported effective against neuronal cell dysfunction and cell death, but again, this has not yet been tested in humans.
Researchers at the Weill Medical College of Cornell University reported that dietary supplementation with resveratrol significantly reduced plaque formation in animal brains, a component of Alzheimer and other Neurodegenerative diseases. In humans it is theorized that oral doses of resveratrol may reduce beta amyloid plaque associated with aging changes in the brain.
respectively. Resveratrol has been found to inhibit platelet aggregation in vitro.
The mechanisms of resveratrol's apparent effects on life extension are not fully understood, but they appear to mimic several of the biochemical effects of calorie restriction. Studies of numerous species have shown that a reduction in calories has been linked to a longer lifespan. The sirt-1 gene activates a critical component of calorie restriction in mammals and promotes fat metabolization. There is evidence that resveratrol may be a calorie restriction mimetic, a compound that mimics the effects of calorie restriction by targeting metabolic and stress response pathways affected by calorie restriction, but without restricting caloric intake, which may be helpful in promoting a longer lifespan.
The lifespan of mice on a high-calorie diet including resveratrol was extended such that their lifespan was similar to that of mice fed a standard diet a recent study reported.
In the test tube, resveratrol effectively scavenges free radicals and other oxidants.
Recently 60 minutes episode highlighted research which suggests that resveratrol can delay the aging process and prevent many gerontological diseases.
In detail this natural substance is being trialed against,
Lactic Acid Buildup, Free Radicals & Dangerous Toxins, Brain and cell degeneration, Carcinogens of all types, Cellular Level dysfunction, Heart Disease, and Stroke Risk.
And to Help Promote,
Metabolic Rate, Good Cholesterol and Natural Energy
As a food supplement resveratrol can be take orally, with a recommended dose of two capsules per day depending on the manufacturer.
Note: It is important to keep in mind that many of the biological activities discussed above were observed in cells cultured in the presence of resveratrol at higher concentrations than those likely to be achieved in humans consuming resveratrol orally.
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